Buffalo Bills vs. New York Jets Preview, Prediction & Odds | Week 2, 2025

A Divisional Matchup, this time in the AFC East, where the New York Jets are taking on the Buffalo Bills at MetLife. These games are always filled with crazy moments, and after all, it is a rivalry matchup. No matter what, knowing these teams, it’s a big game both need to prepare for because it will be filled with passion and pride.

Betting Odds

Team	Spread	Total Over/Under	Money Line
	-6.5 (-110)	Over 47.5 (-110)	-298
	+6.5 (-110)	Under 47.5 (-110)	+240

Apex Tale of The Tape

	Team Stats
41	Points Per Game	32
394	Passing Yards Per Game	218
108	Rushing Yards Per Game	182
497	Total Yards Per Game	394
40	Points Per Game Allowed	34
2	Sacks	4
1	INTs	0
1	TO Ratio	-1
34:49	Time of Possession	34:34

Injuries

Buffalo Bills

OUT

• DT Ed Oliver (Ankle)

Questionable

• S Jordan Hancock (shoulder)
• CB Taron Johnson (quad)
• LB Shaq Thompson (hamstring/ hand)
• TE Dawson Knox (hip)
• DE Greg Rousseau (knee)
• CB Tre’Davious White (groin)
• CB Christian Benford (Groin)
• CB Brandon Codrington (Knee)
• RB James Cook (Hamstring)
• WR Keon Coleman (Groin)

New York Jets

OUT

• WR Josh Reynolds (Hamstring)
• KR/RB Kene Nwangwu (Hamstring)
• DT Jay Tufele (Illness)

Questionable

• CB Ahmad “Sauce” Gardner (Groin)
• TE Mason Taylor (Ankle)
• LB Marcelino McCrary-Ball (Illness)
• S Michael Carter (Shoulder)
• OT Chukwuma Okorafor (Hand)

Key Stats

Buffalo Bills

• The Buffalo Bills have won 8 of their last 10 games against the New York Jets
• Bills own a 70-58-1 all-time record against the Jets
• The Buffalo Bills lead the League in yards per game, passing yards per game & points per game.

New York Jets

• Leads the NFL in rushing play call percentage at 62.9% on offense
• Jets are 4th in the league with an 11.76% sack percentage
• Jets are 4-6 in the last 10 home games against the Bills

Buffalo Bills vs. New York Jets Betting Trends

	Betting Stats
1-0	W/L Last 3	0-1
1-0	ATS	1-0
1-0	O/U	1-0

Prediction

The Jets may have shown some promise last week against the Pittsburgh Steelers, but this week they face a much tougher opponent in the Buffalo Bills. They just beat the Baltimore Ravens, and it’s hard to see the Bills losing to the Jets. Yes, losing Ed Oliver in this game sucks, and the team is still dealing with injuries in the secondary, but the Bills are still stacked on defense. Look at how they came back against the Baltimore Ravens. If they can do that, they can take care of business against the Jets. Take the Buffalo Bills in this game and bet the over on the 47.5 points total for this matchup.

Final Pick

Buffalo Bills (-6.5) & Over 47.5 Points