The Chicago White Sox welcome the Los Angeles Angels to the Windy City. This is Game 2 of a 3-game series to open up the 2025 MLB season. The Pale Hose won on Opening Day, 8-1. It’s the first time Chicago has been above .500 since March 30, 2023. The Halos will be looking to even up the series on Saturday afternoon. Game 3 is scheduled for Sunday afternoon.
Angels vs. White Sox Odds
| Team | Moneyline | Total | Run Line |
| Angels | -158 | 8.5o +102 | -1.5 +110 |
| White Sox | +134 | 8.5u -134 | +1.5 -132 |
| **Odds Subject to Change** |
Game Details
- Game: Los Angeles Angels at Chicago White Sox
- Date and Time: Saturday, March 29, 2025, 1:10 pm CST
- Location: Rate Field (Kentucky Bluegrass), Chicago, Illinois
Key Stats
Los Angeles Angels
The Angels are scheduled to start RHP José Soriano (6-7, 3.42 ERA, 1.20 WHIP in 2024). Soriano has faced the White Sox only one time, going 2 innings and striking out 5 with a walk. LA had the second-worst record in the AL—only behind this Chicago team—and went 31-50 on the Road. The Angels went 2-4 vs the White Sox in 2024, going 2-1 in LA and getting swept 0-3 in Chicago. LA is led by veteran Mike Trout and Jorge Soler, but both went hitless in Game 1. The Halos only had 5 hits, 2 from C Logan O’Hoppe, who homered in the 9th. His blast avoided an embarrassing shutout to a very poor team.
Chicago White Sox
Chicago is scheduled to start RHP Jonathan Cannon (5-10, 4.49 ERA, 1.33 WHIP). Cannon is an impressive 1-0 vs. the Angels lifetime with 14 strikeouts and an ERA of 2.84 in 2 appearances. Chicago had the worst record in MLB last season (41-121) and the worst post-1900 mark. Chicago went 18-63 at home, which is also the worst mark in the big leagues. But Chicago looked good in the opener for new manager Will Venable on Thursday. Sean Burke threw 6 strong innings, and Andrew Benintendi, Lenyn Siosa, and Austin Slater homered. Opening up with the Angels is a blessing for the White Sox.
Prediction
Even though the White Sox looked good on Opening Day, it’s too hard to bet on them. The last time the South Siders lost to the Angels in Chicago was on May 30, 2023. Last season, Chicago outscored LA 15-5 at Home. None of those 3 games saw more than 7 runs. With both starting pitchers having decent success vs. the opponents, runs should be scarce here. The White Sox played more Unders than any team in 2024 (87-67-8, 56.5%). The Angels played 79 Unders, 74 Overs, with 9 Pushes in the Totals market (51.6% Unders) last year. This Angels vs. White Sox Odds Preview and Pick will back an Under at Rate Field.
