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Predictions

Chicago White Sox Vs. Chicago Cubs Preview, Predictions, & Odds | May 18, 2025

Chicago White Sox vs. Chicago Cubs
May 17, 2025; Chicago, Illinois, USA; Chicago Cubs catcher Vidal Brujan (17) hits an RBI-ground rule double against the Chicago White Sox during the fifth inning at Wrigley Field. Mandatory Credit: Kamil Krzaczynski-Imagn Images

Chicago White Sox (14-32) vs. Chicago Cubs (27-19)

Game Details: Sunday May 18, 2025 @ 2:20 pm EST

Location: Wrigley Field in Chicago, Illinois

J. Cannon (R) vs. C. Rea (R)

Where to Watch: MLB.TV

The Chicago White Sox complete the Crosstown Classic at Wrigley Field on Sunday against the Chicago Cubs. The Cubs have taken the first two games thanks to their high-powered offense. While the White Sox have gotten some runs in the series, the Cubs have scored a total of 20 runs in the two games. It won’t get any easier for the White Sox as they face Colin Rea in Sunday’s finale. Can the Cubs complete the sweep, or will the White Sox take one game in the series?

Betting Odds

TeamSpreadTotal RunsMoney Line
Chicago White Sox vs. Cincinnati Reds Preview, Prediction & Odds | May 15, 2025+1.5 (+110)Over 8 (-108)+245
Chicago Cubs logo-1.5 (-130)Under 8 (-112)-305
** Odds Courtesy of DraftKings**

Apex Tale of The Tape

Chicago White Sox vs. Cincinnati Reds Preview, Prediction & Odds | May 15, 2025Team StatsChicago Cubs logo
3.38Runs/G5.71
.217BA.253
.290OBP.329
.329SLG.440
.619OPS.769
36HR65
37SB57
4.15ERA4.00
1.39WHIP1.30
7.53K/98.10
.979Fielding Percentage.985
3Saves10

Projected Starting Pitchers H2H

Jonathan CannonPlayer StatsColin Rea
2-4W/L3-0
3.60ERA2.48
50.0IP36.1
1.36WHIP1.21
39K29
17BB9

Key Stats

Chicago White Sox

The Chicago White Sox once again came out hot with Chase Meidroth hitting a leadoff home run. He went 3 for 4 in the game yesterday. The key stat for the White Sox yesterday is that they were 0 for 1 with RISP. The offense isn’t generating scoring opportunities, getting most of their runs on solo home runs and sacrifice opportunities. Luis Robert Jr. continued his slump, going 0 for 4 in the game. In the last 12 games, he has only six hits, batting an abysmal .143 with 14 strikeouts.

Right-hander Jonathan Cannon takes the mound in the series finale. In his last start against the Cincinnati Reds, he threw 6.0 innings, only surrendering four hits and striking out six. Cannon had a rough April but has settled into a better rhythm in May. In three games pitched with two starts in the month, he has thrown 18.0 innings and only given up four earned runs. The right-hander has given up six home runs this year, all of them on the road.

Chicago Cubs

Pete Crow-Armstrong continued his hot streak for the Chicago Cubs. He is 6 for 10 in the series, with eight RBIs and a home run. Over the past 13 games, he is hitting .320 with four homers and 15 RBIs. Shortstop Dansby Swanson also had a big game for the Cubs yesterday, going 2 for 3 with three runs scored, two walks, and an RBI. On the base paths, the team swiped five bases on Saturday. They are currently second in the majors, only trailing their division rival, the Milwaukee Brewers.

The Cubs are sending out right-hander Colin Rea in the series finale. While his stats look decent, he has had a rough start to the month of May. In three starts, he has pitched 17.2 innings, giving up 18 hits, nine runs, and eight earned runs. He has also walked six batters in that span. Rea will look to get back on track against one of the weaker offenses in the league.

Chicago White Sox vs. Chicago Cubs Betting Trends

Chicago White Sox vs. Cincinnati Reds Preview, Prediction & Odds | May 15, 2025Betting StatsChicago Cubs logo
4-6W/L 105-5
24-22ATS24-22
20-22-4O/U25-16-5

Prediction

The Chicago Cubs have dominated the series so far. The White Sox haven’t made it close, giving up a ton of runs. Many of the Cubs’ hitters are seeing the ball well, and Cannon has struggled on the road. Like the previous two games in the series, I don’t see this one being close.

Final Pick

Chicago Cubs -1.5 (-130)