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Inside Look: Kansas City Chiefs Week 6 Injury Report for 2025 NFL Season

Inside Look: Kansas City Chiefs Week 6 Injury Report for 2025 NFL Season
Sep 28, 2025; Kansas City, Missouri, USA; Kansas City Chiefs wide receiver Xavier Worthy (1) on field for warm ups against the Baltimore Ravens prior to a game during the game at GEHA Field at Arrowhead Stadium. Mandatory Credit: Denny Medley-Imagn Images

The Kansas City Chiefs are facing a potentially significant setback as they prepare for their Sunday night matchup against the Detroit Lions. Wide receiver Xavier Worthy was the sole player absent from Thursday’s practice, dealing with a combination of shoulder and ankle injuries that have cast doubt on his availability.

The mood at the Chiefs facility was one of focused determination, but the absence of their explosive first-round pick was palpable. After being a full participant in Wednesday’s session, Worthy’s status was downgraded to “Did Not Participate” on Thursday, a concerning development for a player who has quickly become a key component of the team’s offense.

A Near Perfect Practice for Kansas City

Aside from Worthy, the Chiefs had a promising day on the injury front. The rest of the 10 players on the report, including quarterback Patrick Mahomes (groin) and linebacker Nick Bolton (calf), were full participants for the second consecutive day.

The return of cornerback Kristian Fulton (ankle) and defensive tackle Omarr Norman-Lott (shoulder) to full practice is a positive sign for a defense looking to be at its best. However, the optimism is tempered by the uncertainty surrounding Worthy. His speed and playmaking ability are crucial to stretching the field and opening up opportunities for other offensive weapons.

Lions Grapple with Extensive Injuries

While the Chiefs navigate Worthy’s status, the Detroit Lions are dealing with a much more widespread injury crisis. Five of their starters did not practice on Thursday, including cornerback Terrion Arnold (shoulder), left tackle Taylor Decker (shoulder), and safety Kerby Joseph (knee).

Star wide receiver Amon-Ra St. Brown (wrist) did return to practice in a full capacity after sitting out Wednesday, providing a glimmer of hope for the Lions’ offense. Still, the sheer number of key players on their injury list presents a major challenge as they head to Arrowhead Stadium.

For the Chiefs, the next 24 hours will be critical. The team and its fans will be anxiously awaiting Friday’s final injury report, hoping for good news on Worthy. His presence on Sunday could be the difference-maker in what promises to be a hard-fought battle between two of the league’s top contenders.