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NFL

Indianapolis Colts vs. Seattle Seahawks Start Em Sit Em Week 15 2025 Fantasy football Breakdown

The Colts are trending downward following the Daniel Jones injury, leaving their offense in question as they head into a tough matchup against the Seahawks.

Jeff Snow photo
By Jeff Snow · Updated · 2 min read
seattle seahawks
Oct 29, 2023; Seattle, Washington, USA; Seattle Seahawks wide receiver Jaxon Smith-Njigba (11) carries the ball after a catch while chased by Cleveland Browns safety Grant Delpit (22) at Lumen Field. Mandatory Credit: Steven Bisig-USA TODAY Sports

The Colts are trending downward following the Daniel Jones injury, leaving their offense in question as they head into a tough matchup against the Seahawks. Seattle, meanwhile, has been able to generate production through its passing game, giving fantasy managers some clear options this week.

Seahawks Starters

QB – Sam Darnold, Seahawks

Darnold put up a big week last week and should have plenty of opportunities against the struggling Colts. He’s a safe start in all fantasy formats.

RB – Jonathan Taylor, Colts

Taylor scored last week and will be heavily leaned on again. Despite Indianapolis’s offensive uncertainty, Taylor remains a workhorse option.

WR – Jaxson Smith-Njigba, Seahawks

Smith-Njigba is the top target-getter for Seattle and scored twice last week. He’s a must-start in all formats.

WR – Cooper Kupp, Seahawks

Kupp continues to turn in scores and should see plenty of targets. Start him confidently this week.

Cooper Kupp goes full Philip Rivers to media before facing 44-year-old QB – Mike Glanakos vis Y Sports

WR Flex – Rasheed Shahid, Seahawks

Shahid drew six targets last week and is carving out a role in Seattle’s offense. He’s a viable flex, especially in PPR leagues.

TE Flex – Tyler Warren, Colts

Whoever is under center for the Colts is expected to target Warren often, giving him upside in deeper leagues.

WR Flex – Michael Pittman, Colts

Pittman has solid talent, but his production is heavily dependent on the quarterback situation. Start with caution.

Colts Sits

week 12
Indianapolis Colts wide receiver Alec Pierce (14) signals a first down after a catch Sunday, Oct. 12, 2025, against the Arizona Cardinals at Lucas Oil Stadium in Indianapolis.

WR – Alec Pierce, Colts

Pierce has potential, but uncertainty at QB makes him a risky play this week.

Alec Pierce Practices infill on Wednesday via Roto Baller

TE – AJ Barner, Seahawks

Barnes has struggled to produce in recent weeks. Sit him until his role becomes clearer.

WR – Josh Downs, Colts

Downs is a no-go this week; hold off until next week for potential production.

Fantasy Takeaway

Seattle’s passing game is the clear fantasy focus this week, with Darnold, Smith-Njigba, and Kupp leading the charge. Rasheed Shahid offers upside as a flex. Colts’ options are riskier due to QB uncertainty with Phillip Rivers coming out of retirement to start, though Jonathan Taylor remains a reliable RB1. Pittman and Pierce are touchdown-or-bust plays, and AJ Barner and Josh Downs should be avoided.

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