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Jacksonville Jaguars vs. Tennessee Titans Start Em Sit Em Week 13 2025 Fantasy Football Guide

Jacksonville Aims for Win No. 8 as Tennessee Tries to Keep Pace.

jacksonville jaguars
Sep 21, 2025; Jacksonville, Florida, USA; Jacksonville Jaguars running back Travis Etienne Jr. (1) during pregame against the Houston Texans at EverBank Stadium. Mandatory Credit: Travis Register-Imagn Images

The Jaguars are rolling after a gritty win last week, and this matchup sets them up for their eighth victory of the season, one that could shape the AFC playoff picture. Tennessee continues to fight, leaning on young playmakers and a developing offense, but Jacksonville enters the week with more momentum and more fantasy-friendly options. Managers should expect solid production across the Jags’ offense, with a few deep-league gems worth monitoring.

START ’EM

Tennessee Titans vs. Los Angeles Rams Preview, Prediction & Odds | Week 2, 2025
Sep 7, 2025; Denver, Colorado, USA; Tennessee Titans quarterback Cam Ward (1) drops back to pass against the Denver Broncos during the first half at Empower Field at Mile High. Mandatory Credit: Ron Chenoy-Imagn Images

Trevor Lawrence — QB, Jaguars

Lawrence looked sharp last week and gets a favorable matchup against a Titans defense that has struggled against efficient passers. Expect a multi-touchdown performance, similar to his most recent outing, with strong QB1 upside.

2025 Art Rooney Award: Jaguars Travis Etienne Jr. Nominated- John Oehser. via Jaguars.com

Travis Etienne (ETN) — RB, Jaguars

ETN remains one of Jacksonville’s most dynamic weapons. He’s tough between the tackles and a big factor in the passing game—his dual-threat role boosts his floor and ceiling. Lock him into your lineup as a top-tier RB start.

Parker Washington — WR, Jaguars

Washington found the end zone last week, and his involvement continues to rise. In leagues with multiple FLEX spots, he holds real value. With his role expanding, Washington is a smart upside play.

Jakobi Meyers — WR, Jaguars

Jacksonville loves feeding Meyers when he’s in rhythm, and he’s trending toward another strong game. Expect sustained volume and a healthy target share. Locked-in FLEX with WR2 potential.

Sleeper: Brenton Strange — TE, Jaguars

Strange finally delivered the breakout performance fantasy managers were waiting for. His athleticism and increasing trust within the offense make him a sneaky TE start with room to climb further.

Cam Ward — QB, Titans

Ward is a baller—plain and simple. While Tennessee still needs to build around him, he brings enough arm talent and off-script playmaking to stay fantasy-relevant. Expect at least one score and fringe QB2 value with upside in the right game flow.

Cam Ward vs. Trevor Lawrence: 3 Bold Predictions For Jaguars-Titans – John Shipley via SI.com

GUYS TO CONSIDER: Deep-League FLEX Plays

Chimere Dike — WR, Titans

Dike has seen his activity rise in recent weeks, culminating in a touchdown last game. If you’re scrambling for a FLEX in a large league, his trend makes him a viable gamble.

Gunner Helm — TE, Titans

Helm drew seven targets last week and has quietly been earning more usage. For TE-premium or very deep formats, he’s a solid FLEX-level option.

FINAL TAKEAWAY

The Jaguars enter this matchup hot and project several strong fantasy plays, from Lawrence and ETN to rising names like Parker Washington and Brenton Strange. Tennessee provides some intriguing deeper-league options, but Jacksonville’s consistent momentum gives its players the edge. A win here pushes the Jags to eight victories and pushes several of their fantasy starters toward big days.